Application of Modelling and Simulation Approaches to Predict Pharmacokinetics of Therapeutic Monoclonal Antibodies in Pediatric Population

Ethical regulations and limited paediatric participants are key challenges that contribute to a median delay of 6 years in paediatric mAb approval.To overcome these barriers, modelling and simulation methodologies have been adopted to design optimized paediatric clinical studies and reduce patient burden.The classical modelling approach in paediatr

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Main problems of the development of fruit and berry raw materials processing industry in the Russian Federation

Food safety is one of the most important and actual problems of the humanity.It is well-known and approved that a country is in safe food situation only in case when it independently produces essential foodstuffs at least 80% of its self-sufficiency level.The current situation is forcing us to achieve the independence from imports.In our research,

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Lapped Block Image Analysis via the Method of Legendre Moments

Research investigating the use of Legendre moments for pattern recognition has been performed in Leggings recent years.This field of research remains quite open.This paper proposes a new technique based on block-based reconstruction method (BBRM) using Legendre moments compared with the global reconstruction method (GRM).For alleviating the blockin

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